Motor impairment in post-stroke depressed patients
Conditions
Interventions
Routine training group:conventional training group
rTMS group :conventional training and left Dlpfc-rTMS
Sham stimulation group:conventional training and left Dlpfc-rTMS sham stimulation
Sponsors
Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The enrolled patients must meet the diagnostic criteria for stroke at the 4th National Conference on Cerebrovascular Diseases: (1) First left subcortical stroke; (2) the presence of hemiplegia; (3) Modified Ashworth Scale (MAS) on the affected side < grade 2; (4) Age 18-80 years old, the course of the disease is between 3-12 months; (5) Mental clarity and stable vital signs; (6) right-handed; (7) SDS = 53 or HAMD = 8; (8) Be informed about the research of this topic and voluntarily sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Brainstem and cerebellar infarction; (2) Osteoarticular and muscular diseases; (3) Other serious neurological diseases; (4) Combined with severe cardiopulmonary, hepatic and renal insufficiency; (5) epilepsy; (6) Severe cramping or pain; (7) Severe speech, attention, hearing, vision, sensory, intellectual, psychiatric or cognitive impairment (MMSE> 24/30 points); (8) Patients with malignant tumor diseases and malignant hypertension; (9) Those who have metal objects or magnetic sheets in the skull, pacemakers, and medically implanted devices such as intracardiac wires and central venous catheters.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain activation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hand grip function;Emotion;Activity of daily living;Brain connectivity;Metabolic changes; | — |
Countries
China
Contacts
Public ContactYan Hua
Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University
Outcome results
None listed