Chronic kidney disease
Conditions
Interventions
walk training with blood flow restriction:walking training with blood flow restriction
walk training:walking training
Usual care:Usual care
Sponsors
Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. adults (age = 18 years), 2. MHD = three months, 3. hemodialysis three sessions per week, 4. ability to walking without assistive from other persons and equipment, 5. ability to understand exercise instruction, and 6. ability to read Chinese.
Exclusion criteria
Exclusion criteria: 1. exercise regularly (i.e., >150 minutes per week of aerobic exercise or structured resistance exercise > one session per week), 2. contraindications to exercise training (e.g., musculoskeletal factors and neurological conditions), 3. higher risk of hemodynamic when conduct exercise: SBP = 180 mmHg or DBP = 105 mmHg before dialysis, rest heart rate = 120 beats per minute, gains above 4 kg of weight since last dialysis/exercise session, symptomatic heart failure, severe arrhythmia, etc., 4. high risk of BFR implementation: coagulation or presence of signs of thrombophlebitis, diagnosis of peripheral vascular disease or with symptoms suggestive of peripheral vascular disease, peripheral edema, skin damage of any low limb, etc., 5. had a single-pool Kt/V (spKt/V) value of < 1.2 [56]. 6. with lower limb deep vein catheterization or lower limb arteriovenous fistula.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-minute walking test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Handgrip strength (HGS);30-second sit-to-stand-to-sit test (STS30);Time up-and-go test (tug);Health-related quality of life;Anxiety;Depression; | — |
Countries
China
Contacts
Public ContactHU Huagang, JIANG Xiaomei, XU Qinjuan
Soochow University; The Second Affiliated Hospital of Soochow University; The First Affiliated Hospital of Soochow University,
Outcome results
None listed