anxiety
Conditions
Interventions
Dexmedetomidine nasal spray group:Use dexmedetomidine nasal spray before going to sleep the night before surgery.
Saline nasal spray group:Use saline nasal spray before going to sleep the night before surgery.
Sponsors
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 18-65, both male and female; (2) Scheduled for breast cancer resection or thyroid cancer resection; (3) Voluntarily participate in this clinical trial, and willingly sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Amsterdam Anxiety Scale score 2 times the upper limit of normal, or total bilirubin >1.5 times the upper limit of normal; (12) Abnormal renal function: participants with screening creatinine >1.5 times the upper limit of normal; (13) Participants allergic to the drug components or ingredients used in this study, such as dexmedetomidine, propofol, opioids, etc.; (14) Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| State anxiety inventory; | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative sleep quality;numerical rating scale;The incidence of postoperative nausea and vomiting;Postoperative recovery quality;Perioperative complications; | — |
Countries
China
Contacts
Public ContactBin Jia
The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Outcome results
None listed