Acute Ischemic Stroke
Conditions
Interventions
Treatment group:EECP
Control group:Sham EECP stimulation
Sponsors
The Second People's Hospital of Hefei
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: ? The diagnostic criteria of AIS were in line with the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018; ? AIS patients were admitted to hospital within 4.5 h of onset and received intravenous infusion of rt-PA; ? Independent daily life before symptom onset, modified Rankin scale (mRS)=2; ? National Institutes of Health Stroke Scale (NIHSS) score = 20; ? All patients included in the study agreed to participate and signed informed consent.
Exclusion criteria
Exclusion criteria: ? mRS Score =2 points after intravenous thrombolysis; ? Previous brain disease, including intracranial aneurysm or arteriovenous malformation, brain surgery or hemorrhagic stroke, dementia ? Previous major diseases: cancer, serious heart disease (left ventricular ejection fraction < 40%, valvular heart disease), acute and chronic severe renal insufficiency; ? cardiogenic cerebral embolism; ? Uncontrolled hypertension (blood pressure =180/100 mmHg); ? Implantable pacemakers, drug pumps and brain stimulators; ? Deep venous thrombosis or coagulation dysfunction of lower limbs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRS score;Mortality;sICH;END; | — |
Secondary
| Measure | Time frame |
|---|---|
| Barthel;The average blood flow velocity of bilateral anterior, middle, and posterior cerebral arteries, as well as the vertebrobasilar artery; | — |
Countries
China
Contacts
Public ContactLong Wang
The Second People's Hospital of Hefei
Outcome results
None listed