Periodontitis and GDM during pregnancy
Conditions
Interventions
Control Group:Daily gum coating with pure water as placebco
DHA Group:DHA products were purchased from Lysineca, which were composed of canola oil (non-GMO) and DHA algal oil. Each 1ml DHA algal oil contained 100mg DHA (docosahexaenoic acid), and the recommend
Sponsors
Wenzhou People's Hospital
Eligibility
Sex/Gender
Female
Age
25 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Pregnant women who are permanent residents of the city, can go to the hospital for prenatal examinations on a regular basis, have informed consent and are willing to cooperate with follow-up follow-up, and have normal language skills. 2. Pregnant women 25 < = age< = 45 years old. 3. Body weight is not less than 45kg, prenatal body mass index (BMI) is between 18.0~28.0 kg/m^2, BMI = weight (kg)/height ^2 (m^2), including the cut-off value. 4. Good physical and mental health, no history of previous major diseases and drug allergies, no systemic diseases, infectious diseases (such as periodontitis, pneumonia, sexually transmitted infections or urinary tract infections), psychiatric diseases, pregnancy diseases or abnormal symptoms (such as preeclampsia) except gestational diabetes.
Exclusion criteria
Exclusion criteria: 1. Participated in other drug clinical trials within 1 month before enrollment. 2. In addition to gestational diabetes, suffering from other pregnancy complications or major systemic diseases. 3. Drinking alcohol and/or smoking within the first six months of pregnancy. 4. Have a history of illegal drug use, take probiotic preparations or use antibiotics within 1 month before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing depth, PD;Fasting blood gluose; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gingival index, Gl;Attachment loss, AL;Plaque index, PLI; | — |
Countries
China
Contacts
Public ContactLi Xiaoqing;Wang Jinfeng
Wenzhou People's Hospital
Outcome results
None listed