Infratentorial Lesions(VENTIL)
Conditions
Interventions
Experimental group:Early tracheostomy is performed within 2 days of surgery
Control group:Standard tracheostomy is performed 2 days postoperatively
Sponsors
Sanbo Brain Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria 1. Informed consent by the patient and/or legal proxy 2. Age 18 years or older 3. Patients underwent infratentorial lesions within 48 hours post-surgery 4. VENTIL Score =6 points
Exclusion criteria
Exclusion criteria: Exclusion Criteria 1) Neurofibromatosis NF2 2) Severe brain hemorrhage 3) Pre-operative severe pneumonia 4) Premorbid modified Rankin Scale (mRS) >1 5) Pregnancy 6) Expected need for a permanent surgical tracheostomy 7) Participation in any other interventional trial 8) Life expectancy or consideration of transition to comfort measure only within half a year
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| body temperature;CT chest;clinical chemistry; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved Rankin scale;Length of ICU stay;Time to successful tracheal extubation;Duration of sedation; | — |
Countries
China
Contacts
Public ContactChang-xiang Yan
Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing 100050, China.
Outcome results
None listed