Cardiovascular disease
Conditions
Interventions
the test group:Shexiang Tongxin drop pills
the controlled group:The Placebo of Shexiang Tongxin drop pills
Sponsors
Dongzhimen Hospital, Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1) Meeting the diagnostic criteria for Stemi and NSTEMI, 2) Patients aged between 18 to 85 years, 3) Patients volunteered inclusion to participate in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: Patients with any of the following conditions were not included in the study will be excluded: 1) Cardiogenic shock; 2) A previous history of heart failure; 3) Uncontrolled hypertension (SBP > 180 mmHg or DBP > 110 mmHg) despite medication; 4) Patients who have an increased risk of bleeding, such as those with a history of hemorrhagic stroke, cerebral aneurysm, trauma or major surgery within the past month (including bypass surgery), or those with a current disease that causes active bleeding. 5) Patients with congenital heart defects, severe valvular heart disease, malignant tumors, or severe mental illness. 6) Patients with severe hepatic and renal dysfunction, indicated that ALT or AST levels =3×ULN (upper limit of normal), or TBIL =2×ULN, orCcr<30ml/min. 7) Women who are planning to become pregnant, currently pregnant, or lactating. 8) Patients with an allergic constitution, or those with food allergies to multiple drugs, or those who are allergic to the experimental drugs being used in the study (including their components). 9) Participants who have been involved in other clinical trials within the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular end-systolic volume index;End Diastolic Volume;Left Ventricular Ejection Fraction;Bore in left ventricular end-diastolic stage;Plasma level of RIP1;Plasma level of RIP3;Plasma level of MLKL; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of the composite end point of main adverse cardiac events;Left ventricular volumes;Left ventricular mass index;Minnesota living with heart failure questionnaire;NT-proBNP;hsCRP;TNF-a;IL-6; | — |
Countries
China
Contacts
Public ContactJingen Li
Dongzhimen Hospital, Beijing University of Chinese Medicine
Outcome results
None listed