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Application of Bupivacaine Liposome Pericapsular Nerve Group(PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia After Total Hip Arthroplasty

Application of Bupivacaine Liposome Pericapsular Nerve Group(PENG) Block Combined with Lateral Femoral Cutaneous Nerve Block for Postoperative Analgesia After Total Hip Arthroplasty

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080696
Enrollment
Unknown
Registered
2024-02-05
Start date
2024-02-05
Completion date
Unknown
Last updated
2025-03-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

total hip arthroplasty

Interventions

A Group (Ropivacaine Group):Application of 100mg:25ml (0.4%) ropivacaine pericapsular nerve group(PENG) block combined with lateral femoral cutaneous nerve block
B Group (Bupivacaine Liposome Group):Application of 266mg:25ml (1.06%)bupivacaine liposome pericapsular nerve group(PENG) block combined with lateral femoral cutaneous nerve block
B2 Group ( liposomal bupivacaine combined with bupivacainehydrochloride group):PENG block combined with lateral femoral cutaneous nerveblockwas performed with bupivacaine liposome 266 mgmixedwith0.75%

Sponsors

The First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Aged >= 18 years. 2. American Society of Anesthesiologists (ASA) classification I-III. 3.NYHA classification of cardiac function I-II. 4. Body mass index (BMI) is 18-30 kg·m^2.

Exclusion criteria

Exclusion criteria: 1. Infection at the injection site. 2. Patients have severe arrhythmias or cardiovascular disease, liver and kidney dysfunction, respiratory and coagulation disorders. 3. Continue to take pain relievers in the near future. 4. Having trouble communicating and not being able to complete the scores properly. 5. I or its authorized person does not accept, can not cooperate with block patients have.

Design outcomes

Primary

MeasureTime frame
Visual Analog Scale (VAS) scores;quality of recovery-15 scale (QoR-15);

Secondary

MeasureTime frame
Postoperative adverse events;

Countries

China

Contacts

Public ContactHeng Rong

The First Affiliated Hospital of Guangxi Medical University

heng_rong@sr.gxmu.edu.cn+86 139 7869 6763

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026