Spinal Surgery
Conditions
Interventions
Group B:sodium oxybutyrate combined with propofol
Sponsors
Department of Anesthesiology, Tsinghua University Yuquan Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 40-80 years old; 2. Spinal surgery is to be performed under general anesthesia, and the expected operation time is =2 hours; 3. A self-controlled intravenous analgesic pump is needed after surgery.
Exclusion criteria
Exclusion criteria: 1. Preoperative communication is not possible due to visual, auditory, language or other reasons; 2. Spinal orthopaedic surgery; 3. Patients with severe bradycardia (HR<50 beats/min), sick sinus syndrome, grade 2 or above atrioventricular block without pacemaker implantation; 4. Severe liver function impairment (Child-Pugh grade C); 5. Renal failure (requiring kidney replacement therapy); 6. Participate in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemodynamics;Postoperative pain score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quantity of each drug used in perioperative period;Intraoperative adverse events;Postoperative delirium score;PCA dosage;Patient satisfaction score;Major post-operative laboratory results; | — |
Countries
China
Contacts
Public ContactFan Ting
Department of Anesthesiology, Tsinghua University Yuquan Hospital
Outcome results
None listed