Lumbar spine diseases
Conditions
Interventions
Gold Standard:Patients were divided into two groups according to the percentage change in cardiac index (CI) of Trendelenburg test: ?CITREND= 8% was defined as volume response group
?CITREND <8% was defined as volume non-responsiveness group.
Index test:Efficacy measures (primary and secondary efficacy measures)
Main outcome measures: ?VIJVR TVC6-8
Secondary outcome: VIJVRbase
Safety measures
Invasive blood pressure (IBP), heart rate (HR),
Sponsors
Nanjing Drum Tower Hospital, The Afliated Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) aged 18-75 years; 2) Lumbar surgery in prone position under general anesthesia; 3) agree to participate in the study and sign the informed consent;
Exclusion criteria
Exclusion criteria: 1) refuse to participate in the study; 2) ASA grade =IV; 3) body mass index >30kg/m2, or <18 kg/m2; 4) arrhythmia, cardiac insufficiency, heart valve disease; 5) severe respiratory diseases; 6) increased intracranial pressure and intraocular pressure; 7) Arterial puncture and internal jugular vein puncture were contraindicated; 8) unclear internal jugular vein imaging by ultrasound; 9) other conditions considered by the investigator or physician in charge to be inappropriate for study participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ?VIJVR TVC6-8;cardiac index; | — |
Secondary
| Measure | Time frame |
|---|---|
| VIJVRbase; | — |
Countries
China
Contacts
Public ContactJinhua Bo
Nanjing Drum Tower Hospital, The Afliated Hospital of Nanjing University Medical School,
Outcome results
None listed