diabetic macula edema
Conditions
Interventions
Subthreshold micropulse laser group:Subthreshold micropulse laser
Vitreous cavity injection of anti-VEGF drug group:Vitreous cavity injection of anti-VEGF drugs
Sponsors
The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old; 2. Patients who underwent vitrectomy for PDR at our hospital; 3. At least 1 optical coherence tomography (OCT) scan within 3 months after vitrectomy suggesting macular edema, i.e., CRT = 300 µm and/or subretinal fluid and/or intraretinal fluid within 500 µm of the center of the macula with a CRT 0.05 (decimalized); 5. Consent to participate in the study
Exclusion criteria
Exclusion criteria: 1. Combined retinal vein occlusion, uveitis, ocular trauma, age-related macular degeneration or other ocular or systemic conditions that may cause macular edema: 2. Have received vitreous cavity drug injections after vitrectomy or postoperatively ; 3. re-supplemental retinal laser photocoagulation after vitrectomy; 4. silicone oil filled eyes; 5. Re-vitrectomy; 6. follow-up for less than 6 months; 7. women during pregnancy or lactation; 8. Those who cannot cooperate due to major systemic diseases such as stroke, cardiovascular and cerebrovascular accidents or other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| central retinal thickness;best-corrected visual acuity;number of treatments with sub-threshold micropulse laser group;number of treatments in the vitreous cavity injection of anti-VEGF drug group; | — |
Secondary
| Measure | Time frame |
|---|---|
| morphological structure of macular OCT;microvision;adverse events during follow-up; | — |
Countries
China
Contacts
Public ContactLin Zhong
The Eye Hospital, School of Ophthalmology and Optometry, Wenzhou Medical University
Outcome results
None listed