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Central mechanism study of contralateral benefit from occupational therapy training

Central mechanism study of contralateral benefit from occupational therapy training

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080659
Enrollment
Unknown
Registered
2024-02-04
Start date
2024-02-19
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Health Control Group:Contralateral training(motor skill / strength training)
Stroke Experimental Group:Contralateral training(motor skill / strength training)

Sponsors

Sir Run Run Hospital, Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Stroke 1.The diagnosis of stroke was in line with the diagnostic points of various cerebrovascular diseases adopted by the Fourth National Conference on Cerebrovascular Diseases in 1995, and the diagnosis of stroke was confirmed by head CT or MRI examination ; 2.Duration of onset =2 weeks, the presence of upper limb motor dysfunction;3.Before onset, she was right-handed and had no obvious cognitive dysfunction, with MMSE=25 points;4.Skull intact, no craniotomy or cranioplasty;5. Volunteer to cooperate with participants who were followed up for three times of NIR brain functional imaging equipment collection and cognitive assessment before and after the training and one week later;6. Able to understand the purpose of the research, cooperate with the research, and sign the informed consent. Health 1. Age =18 years old; 2. Those who are judged as right-handed by the Chinese Left and Right Handedness Examination Scale; 3.People without obvious cognitive impairment or serious neurological diseases that may have an impact on the study results; 4. Volunteer to cooperate with participants who were followed up three times before and after the training and one week later to collect fNIRS functional brain imaging equipment and cognitive assessment; 5. Able to understand the purpose of the research, cooperate with the research, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1.People who have obvious mental and mood disorders , or have a history of neurological diseases and psychosis;2.Have a history of seizures or convulsions;3.People with severe dementia or speech problems who are unable to cooperate on tasks;4.Concomitant with any neurological or musculoskeletal disorders affecting cognitive function;5.Progressive aggravation of the disease

Design outcomes

Primary

MeasureTime frame
motor performance;Fulg-Meyer Assessment;Purdue Pegboard test;

Secondary

MeasureTime frame
HbO;functional connectivity;motor evoked potential;

Countries

China

Contacts

Public ContactFeng Lin

Department of Rehabilitation Medicine, Sir Run Run Hospital, Nanjing Medical University

peterduus_lin@hotmail.com+86 138 5144 6615

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026