halitosis
Conditions
Interventions
Probiotic group:Probiotic toothpaste
Sponsors
The Affiliated Stomatological Hospital of Xiamen Medical College
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: A. The concentration of volatile sulfur compounds (VSC) in oral air is =100ppb; B. No untreated patients with other oral diseases; C. Good adherence to oral hygiene instructions, there are more than 20 natural teeth in the mouth; D. People who are able to understand clinical studies and are committed to complying with study requirements and procedures; E. People who have signed informed consent forms. Able to complete the study according to the requirements of the test protocol.
Exclusion criteria
Exclusion criteria: A. The use of probiotic products with similar functions to those tested within 2 days affects the judgment of the results; B. Patients who had taken antibiotics 2 weeks before recruitment; C. Poor, unsatisfactory oral hygiene and lack of compliance among people; D. Patients with oral tumors; E. cannot meet the fasting or abstinence requirements for the assessment period due to medical reasons. F. Use phenol-containing or peppermint flavoring products, such as mouthwash, chewing gum, etc.; G. Smoking or using tobacco products; H. no digestive system, respiratory system and other diseases, no other systemic diseases; I. In the investigator's judgment, the subject's condition does not qualify him for study; J. Women during pregnancy, lactation or menstruation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VSC; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sequencing of tongue moss flora;Sequencing of salivary flora; | — |
Countries
China
Contacts
Public ContactLiang Zhao
The Affiliated Stomatological Hospital of Xiamen Medical College
Outcome results
None listed