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Effect of thoracic paravertebral nerve block with different concentrations of ropivacaine on postoperative analgesia in patients undergoing single-port thoracoscopic surgery: a randomized controlled trial

Effect of thoracic paravertebral nerve block with different concentrations of ropivacaine on postoperative analgesia in patients undergoing single-port thoracoscopic surgery: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080654
Enrollment
Unknown
Registered
2024-02-04
Start date
2024-02-10
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thoracic diseases

Interventions

GroupR1:0.25% Ropivacaine 30ml+ dexamethasone 0.15mg/kg thoracic paravertebral nerve block
GroupR2:0.375% Ropivacaine 30ml+ dexamethasone 0.15mg/kg thoracic paravertebral nerve block
GroupR3:0.5% Ropivacaine 30ml+ dexamethasone 0.15mg/kg thoracic paravertebral nerve block

Sponsors

Chengdu Shangjin Nanfu Hospital-West China Shangjin Branch Department of Anesthesiology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: a) Patients undergoing elective thoracoscopic surgery under general anesthesia; b) Obtain the informed consent of the patient or the patient's family to receive regional nerve block and postoperative controlled intravenous analgesia; c)ASA grade I-II; d) Ages 18 to 65. e)BMI: 18-30 kg/m2

Exclusion criteria

Exclusion criteria: a) Abnormal spinal or paravertebral anatomy; b) Skin infection at the puncture site; c) Allergic to local anesthetics; d) Abnormal coagulation function; e) History of acute chronic pain or long-term use of sedative and analgesic drugs; f) severe hepatic and renal insufficiency; Severe respiratory and circulatory diseases; g) neurological or mental disorders; h) Pregnancy.

Design outcomes

Primary

MeasureTime frame
VAS scores at different time points after surgery;Time of first compression of patient's analgesic pump;Morphine consumption in 48h after surgery;

Secondary

MeasureTime frame
Opioid-related adverse reactions;Incidence of local anesthetic poisoning after block;Pittsburgh Sleep Quality Index score;

Countries

China

Contacts

Public ContactRurong Wang

Anesthesiology Department, 5th Floor, Chengdu Shangjin Nanfu Hospital, Chengdu High-Tech West District, Chengdu, Sichuan, China

wangrurong@scu.edu.cn+86 189 8060 1563

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026