Anesthesia of patients undergoing colonoscopy
Conditions
Interventions
RN group: Remazolam + Nalbuphine:Sedation and anesthesia with remazolam
PN group: Propofol + Nalbuphine:Sedation and anesthesia with Propofol
Sponsors
The Second Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Patients requiring colonoscopy (2) Patients participated in the study knowingly and voluntarily, and signed the informed consent (3) Aged between 18 and 65 (4)ASA classification II-III (5) Body mass index (BMI) =28kg/m^2 (6) When aspirating air (SpO2) > 90%
Exclusion criteria
Exclusion criteria: (1) Difficult airway (there may be factors such as mask difficulty and difficulty in cannulation, such as dentition change, coercive spondylitis, Pierre-Robin syndrome, Mallampati score =?, etc.) (2) Complicated with severe arrhythmia (3) Allergic reaction to the drugs used in this study (4) Patients with contraindications to the drugs used in this study (5) There are serious lung diseases, such as COPD, respiratory failure (6) Patients with severe chronic heart failure (7) Patients with severe hepatic and renal insufficiency (8) Patients with severe chronic pain (9) A history of sedative and analgesic drug dependence (10) Patients with serious mental and nervous system diseases (11) Pregnant women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient's intraoperative vital signs;Qor-15 scale score;VAS pain score;Recovery time of patients; | — |
Countries
China
Contacts
Public ContactLi Luchen
The Second Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed