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Mechanism of Action and Clinical Translational Application of aescin in the Treatment of Helicobacter pylori-Associated Gastric Ulcers

Mechanism of Action and Clinical Translational Application of aescin in the Treatment of Helicobacter pylori-Associated Gastric Ulcers

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080622
Enrollment
Unknown
Registered
2024-02-02
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric ulcer

Interventions

Intervention group:Standard treatment for gastric ulcers and Helicobacter pylori + aescin intervention group
Standard treatment group:Standard treatment for gastric ulcers and Helicobacter pylori

Sponsors

The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1: patients whose age are greater than or equal to 18 years old and younger than or equal to 75 years, gender is not limited 2: Patients who can consent and sign an informed consent form 3: Patients diagnosed with benign gastric ulcers through gastroscopy examination 4: Patients who have undergone C13 or C14 breath test or rapid urease test during endoscopy examination

Exclusion criteria

Exclusion criteria: 1: Patients diagnosed with gastric precancerous lesions (dysplasia/intraepithelial neoplasia) or gastric cancer through gastroscopy and/or pathological examination 2: Patients currently participating in other clinical trials of medications 3: The researcher believes that the patient has potential risks or any other factors that may interfere with the patient.

Design outcomes

Primary

MeasureTime frame
Gastroscopy examination;

Secondary

MeasureTime frame
liver function;kidney function;blood routine examination;C13/C14 breath test;Gastric Tissue Rapid Urokinase Assay;electrocardiographic examination;

Countries

China

Contacts

Public ContactFangmei An

Department of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University

wdf8025@163.com+86 133 8224 1680

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026