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Characteristics of central and peripheral synchrony oxygenation during grasping and the rehabilitation mechanism of motor function of upper extremity in people with stroke

Characteristics of central and peripheral synchrony oxygenation during grasping and the rehabilitation mechanism of motor function of upper extremity in people with stroke

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080619
Enrollment
Unknown
Registered
2024-02-02
Start date
2022-04-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Intervention group A (could grasp 2.5cm3 blocks):VR training combined with traditional OT
Intervention group B (could grasp 5cm3 blocks):VR training combined with traditional OT
Intervention groupC (could grasp 10cm3 blocks):VR training combined with traditional OT

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: ? First stroke, confirmed by CT or MRI examination, with one side of the upper limb motor dysfunction but clinically stable patients; ? 40~80 years; ? The duration of the disease is less than 3 months; ? the score of the Glass Coma Score Scale is greater than 10, no severe cognitive dysfunction (MMSE =22), and can accept motor commands; ? Can maintain an upright position on an armless seat for =30 minutes; ? Improved Ashworth grade of the right upper limb = grade 2; ? The Brunnstrom function grade of the affected side hand is =3, and it has a certain grasping function, and can grab at least a wood block with a side length of 2.5cm after efforts; ? The patient and his family members agree to be enrolled and sign the informed consent.

Exclusion criteria

Exclusion criteria: ? The clinical condition is unstable; ? Any neuropsychiatric illness other than stroke; ? Schizophrenia, bipolar disorder, obsessive-compulsive disorder or personality disorder and major depression; ? Skin lesions and infections;? Fracture of the upper limb, or deformity or absence of the finger on the affected side.

Design outcomes

Primary

MeasureTime frame
Functional near infrared spectroscopy;Functional near infrared spectroscopy;

Secondary

MeasureTime frame
fMRI;MEP;ARAT;FMA-UE;MyotonPRO;MBA;MBI;

Countries

China

Contacts

Public ContactZhao Jiangli

The First Affiliated Hospital of Sun Yat-sen University

zhaojl6@mail.sysu.edu.cn+86 134 3020 4648

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026