Gastric Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed with gastric cancer through pathological examination; (2) Age 18-80 years old; (3) Prior to this experiment, no surgery, radiotherapy, chemotherapy, or other treatments were received; (4) No use of antibiotics in the short term (5)The patient and his family members informed consent to this study, and signed an informed consent form
Exclusion criteria
Exclusion criteria: 1) Those who are deemed unsuitable to participate in this trial by a physician; 2) Patients with ischemic heart disease, cerebrovascular disease, and peripheral vascular disease, patients with heart function>Level II (NYHA), patients who have recently undergone CABG surgery, and patients with severe hypertension (systolic blood pressure = 180mmHg or diastolic blood pressure = 110mmHg); 3) Patients with distant metastasis of the tumor; 4) Patients with severe infection, respiratory dysfunction, coagulation dysfunction, and severe liver and kidney dysfunction (Child Pugh = 10 points; creatinine clearance rate10%, or SGA nutritional status evaluation grade C, BMI<18, Hb<70g/L); 9) Used antibiotics or supplemented probiotics before the experiment; 10) Patients with severe edema, infection, and peripheral blood circulation disorders; 11) Pregnant and lactating women, subjects (including male subjects) who have a pregnancy plan within one month after the trial, 12) are unable to complete accelerated rehabilitation surgery procedures or have obvious contraindications to accelerated rehabilitation surgery; 13) Participate in other clinical trials within 3 months prior to the trial; 14) Applicants or researchers directly participating in the experiment or their family members.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount of tryptophan in feces ;The amount of indole in feces ;Structure and quantity of gut microbiota ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative complication rate ;hospital stay ;Hospitalization expenses; Immune indexes;Inflammatory indexes;Nutritional indexes;The recovery of intestinal function; | — |
Countries
China
Contacts
Affiliated Hospital of Jiangsu University