Type II respiratory failure
Conditions
Interventions
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: ? Age =18 years old; ? Patients admitted to hospital for mild to moderate acute type II respiratory failure (PaCO2 > 50mmHg with PH > 7.25) requiring respiratory support but no invasive ventilation for the time being; ?Sequential breathing support was proposed for patients undergoing invasive mechanical ventilation for acute type II respiratory failure through an autonomous breathing test. ? and ? conform to one item.
Exclusion criteria
Exclusion criteria: ? Severe respiratory acidosis PH < 7.25; ?HFNC or NIV treatment contraindication: such as oral and facial trauma, nasal obstruction, oral secretions with more and poor clearance ability, hemodynamic serious instability; ?Patients with very poor near-term prognosis, greater risk of death within one week, or those undergoing hospice; ? Acute severe failure of other organ functions; ? Tracheotomy; ? Invasive ventilation without off-line extubation conditions; ? Unable to obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HFNC Predictive Model Efficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory rate;saturation of pulse oximetry;heart rate;fraction of inspired oxygen;pH value;arterial partial pressure of oxygen;partial pressure of carbon dioxide;Length of ICU stay;Total length of stay; | — |
Countries
China
Contacts
Public ContactDingyu Tan
Northern Jiangsu People's Hospital
Outcome results
None listed