parturients who are scheduled for elective cesarean delivery
Conditions
Interventions
Group Preterm 1:Intravenous prophylactic infusion of phenylephrine 0.25 µg/kg/min
Group Preterm 2:Intravenous prophylactic infusion of phenylephrine 0.35 µg/kg/min
Group Preterm 3:Intravenous prophylactic infusion of phenylephrine 0.45 µg/kg/min
Group Preterm 4:Intravenous prophylactic infusion of phenylephrine 0.55 µg/kg/min
Group Preterm 5:Intravenous prophylactic infusion of phenylephrine 0.65 µg/kg/min
Group full-term 1:Intravenous prophylactic infusion of phenylephrine 0.25 µg/kg/min
Group full-term 2:Intravenous prophylactic infusion of phenylephrine 0.35 µg/kg/min
Group full-term 3:Intravenous prophylactic infusion of phenylephrine 0.45 µg/kg/min
Group full-term 4:Intravenous prophylactic infusion of phenylephrine 0.55 µg/kg/min
Group full-term 5:Intravenous prophylactic infusion of phenylephrine 0.65 µg/kg/min
Sponsors
Womens' Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: ASA Class II, single pregnancy, elective cesarean section
Exclusion criteria
Exclusion criteria: ASA=III, obesity (body mass index =35kg/m2), presence of neuraxial anesthesia contraindications, hypersensitivity to phenylephrine, gestational hypertension, diabetes, cardiovascular disease, placenta previa, rupture of fetal membrane, and fetal congenital malformations ,being included in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whether hypotension occurs between spinal anesthesia and fetal delivery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in maternal blood pressure and heart rate;neonatal outcome; | — |
Countries
China
Contacts
Public ContactLiHong Sun
Women's Hospital, School of Medicine, Zhejiang University
Outcome results
None listed