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Effect of degenerative spondylolisthesis on the clinical outcome of unilateral biportal endoscopy for lumbar spinal stenosis: a single-center, prospective cohort trial protocol

Effect of degenerative spondylolisthesis on the clinical outcome of unilateral biportal endoscopy for lumbar spinal stenosis: a single-center, prospective cohort trial protocol

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080597
Enrollment
Unknown
Registered
2024-02-02
Start date
2024-03-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lumbar Spinal Stenosis with/without degenerative spondylolisthesis

Interventions

Degenerative lumbar spondylolisthesis group:None
No degenerative lumbar spondylolisthesis group:None

Sponsors

Beijing Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1) Age range: 50–80 years 2) The predominant manifestation is neurogenic intermittent claudication, and conservative treatment has been ineffective for at least 3 months 3) Single segment lumbar spinal stenosis combined with = I degree degenerative lumbar spondylolisthesis; 4) No obvious spinal instability 5) Patients agree to participate in the study and are willing to complete the follow-up

Exclusion criteria

Exclusion criteria: 1) Degenerative lumbar spondylolisthesis of greater than II degree 2) Instability at the response level (slippage more than 3 mm or intervertebral angle change more than 15° in Standing Flexion-extension radiograph) 3) Prior surgical history at the response level 4) Severe scoliosis with Cobb angle >20 degrees 5) Other conditions affecting the lumbar spine such as ankylosing spondylitis, tumor, fracture, neurological diseases 6) Patients with mental disorders 7) Patients have participated in other clinical research projects related to the treatment for lumbar spinal stenosis

Design outcomes

Primary

MeasureTime frame
ODI score;

Secondary

MeasureTime frame
JOA score;VAS leg pain;VAS back pain;SF-36 score;Lumbar X-ray;Lumbar CT;Lumbar MRI;CK;ESR;Modified MacNab score;

Countries

China

Contacts

Public ContactXiang Li

Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University

muzixiangxin2022@163.com+86 136 7135 5062

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026