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The role of intestinal flora changes in heat acclimatization of soldiers stationed in high temperature and humidity environment and its related mechanism

The role of intestinal flora changes in heat acclimatization of soldiers stationed in high temperature and humidity environment and its related mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080567
Enrollment
Unknown
Registered
2024-02-01
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heat acclimatization

Interventions

Observation group:No intervention

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1) Age range from 18 to 35 years old, regardless of gender; 2) Healthy body, normal weight, with a body mass index (BMI) of 18.5-24.9 kg/m2; 3) No history of gastrointestinal diseases such as ulcerative colitis; 4) No history of gastrointestinal tumors or inflammatory diseases, no severe organic lesions such as heart, liver, kidney, lungs, and brain; 5) Not taking any acid suppressants, gastrointestinal motility drugs, antibiotics, or gut microbiota preparations (such as yogurt) within the past 4 weeks; 6) No known infectious diseases; Has not been to an area with locally transmitted diarrhea within the past 6 months; 7) Sign an informed consent form and agree to participate in this study.

Exclusion criteria

Exclusion criteria: 1) History of autoimmune diseases and digestive system surgery; 2) Specific reactive diseases, such as eczema, asthma, and gastrointestinal eosinophil related diseases; 3) The use of antibiotics, drugs that cause disruption of intestinal microbiota, and any immunosuppressants within the past three months.

Design outcomes

Primary

MeasureTime frame
Macrogenomic differences in gut microbiota of fecal samples;

Secondary

MeasureTime frame
Heart rate;Blood pressure;Body temperature;Stool property;Gastrointestinal symptoms;Sleep;Fatigue;Psychological symptoms;Blood\fecal metabolites differences;

Countries

China

Contacts

Public Contactweiyanling

Department of Gastroenterology, Army Medical Center of PLA

lingzi016@126.com+86 153 1035 4666

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026