Subanesthetic esketamine for the prevention of emergence agitation among patients undergoing orthognathic surgery

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400080566

Enrollment

Unknown

Registered

2024-02-01

Start date

2024-02-19

Completion date

Unknown

Last updated

2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

emergence agitation

Interventions

esketamine group:esketamine

control group:saline

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: (1) aged 18-60 years with BMI among 18-30 kg/m2 (2) scheduled to undergo elective orthognathic surgery (3) ASA I-II (4) volunteered to join the study and signed the Informed consent

Exclusion criteria

Exclusion criteria: (1) patients who had taken sedative or hypnotic drugs within 30 days prior to surgery (2) previous history of mental disease and receiving treatment (3) with history of drug/alcohol abuse (4) with contraindication or allergic history to research drug (5) with severe dementia and other communication disorders

Design outcomes

Primary

Measure	Time frame
Incidence of emergence agitation;	—

Secondary

Measure	Time frame
emergence time;extubation time;Cough score;Sleeping quality;Anxiety and depression status;	—

Countries

China

Contacts

Public ContactTong Cheng

Peking University Hospital of Stomatology

chengtong@foxmail.com+86 158 1122 9030

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026