Breast cancer
Conditions
Interventions
Case series:None
Sponsors
Peking University Cancer Hospital (Beijing Institute for Cancer Research)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Invasive breast cancer diagnosed by pathological histology; 2.Aged 18-70; 3.Tumor size>2cm in ultrasound; 4.Estrogen receptor/ Progesterone receptor negative, or human epidemal growth factor receptor-2 positive; 5.ECOG score 0-1, Hematological index and ECG Meet chemotherapy criteria.
Exclusion criteria
Exclusion criteria: 1. Primary stage IV breast cancer; 2. The patient cannot tolerate chemotherapy; 3. Received chemotherapy within 12 months; 4. Suffer from diabetes and other chronic metabolic diseases; 5. Refuse to participate in this study without signing the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Preliminary screening of differential metabolites between chemotherapy sensitivity and resistance;Qualitative and quantitative detection of specific differential metabolites; | — |
Secondary
| Measure | Time frame |
|---|---|
| In vitro measurement of tumor cell invasiveness;Assay of invasive power of implanted tumors; | — |
Countries
China
Contacts
Public ContactWei Cao
Peking University Cancer Hospital (Beijing Institute for Cancer Research)
Outcome results
None listed