Pregnancy loss
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Establishing prospective cohort studies, Exposure group: Women aged 18-45 who have lost at least one pregnancy. Non exposure group: at least one normal live birth in multiple centers, and no adverse pregnancies such as pregnancy loss have occurred (including intrauterine fetal death, stillbirth, fetal miscarriage, ectopic pregnancy, molar pregnancy, etc.), with no serious obstetric complications; No active autoimmune diseases within 3 months; Normal menstrual cycle; Age range from 18 to 45 years old.
Exclusion criteria
Exclusion criteria: The exclusion criteria for the exposed and non exposed groups in queue studies are consistent Have a history of taking anticoagulants, immunomodulators, and steroid drugs within the past 3 months; Patients who refuse to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 weeks live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Early pregnancy loss rate;Clinically confirmed pregnancy rate;Ongoing pregnancy rate(to 10 weeks);Ongoing pregnancy rate(to 12 weeks);28 weeks live birth rate;Ectopic pregnancy rate;Stillbirth rate;Incidence rate of pregnancy complications;Neonatal weigh;Neonatal Apgar score;Neonatal birth defect rate; | — |
Countries
China
Contacts
The Second hospital of Lanzhou University