Hyperplasia prostate
Conditions
Interventions
Normal Saline group (NS group):Normal Saline group (NS group) received 50 m L/h of normal saline, a continuous infusion for 10 min, and a maintenance dose of 10 mL / h.
Low-dose dexmedetomidine group (Group D1):Low-dose dexmedetomidine group (Group D1): Dexmedetomidine 0.4 ug / kg loading dose, 0.2 ugkg-1 h-1 maintenance dose
Medium Dose dexmedetomidine group (group D2): Medium Dose dexmedetomidine group (group D2): Dexmedetomidine 0.4 ug / kg loading dose, 0.4 ugkg-1 h-1 maintenance dose
High Dose dexmedetomidine group (group D3):High Dose dexmedetomidine group (group D3): Dexmedetomidine 0.4 ug / kg loading dose, 0.6 ugkg-1 h-1 maintenance dose
Sponsors
Ya 'an People's Hospital
Eligibility
Sex/Gender
Male
Age
65 Years to 100 Years
Inclusion criteria
Inclusion criteria: ? Age = 65 years; ? ASA grade?-?; ? elective electrosurgical prostate; ? body mass index (BMI): 18-24kg / m2;
Exclusion criteria
Exclusion criteria: ? patients and family members refused; ? ASA grade ?-?; ? heart failure, severe arrhythmia, severe bradycardia (HR below 40 beats / min), atrioventricular block above degree II and morbid sinus syndrome; ? severe hepatic and renal dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mean arterial pressure;postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate ;Number of intraoperative cardiovascular medications administered;Duration of awakening period;peri-arousal mania;Remedial analgesia;postoperative nausea and vomiting; | — |
Countries
China
Contacts
Public ContactZhou Shuzhi
Ya 'an People's Hospital
Outcome results
None listed