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The effect of synchronized tDCS in lower limb rehabilitation robot training on the motor function of hemiplegic lower limbs after stroke and the mechanism of brain limb collaborative regulation

The effect of synchronized tDCS in lower limb rehabilitation robot training on the motor function of hemiplegic lower limbs after stroke and the mechanism of brain limb collaborative regulation

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080500
Enrollment
Unknown
Registered
2024-01-31
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

Test group:Lower limb rehabilitation robot training synchronization tDCS, which means synchronously receiving tDCS during lower limb rehabilitation robot training
control group:Provide tDCS false stimulation during lower limb rehabilitation robot training.

Sponsors

Guangzhou Panyu Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: ? Meets the diagnostic criteria for stroke established in 2019, and is diagnosed with cerebral infarction or cerebral hemorrhage through head CT or MRI; ? First onset, stable vital signs, course of disease 2-6 months, age 40-75 years; ? Hemiplegia on one side of the limb, with Holden's classification of walking ability as Grade I; ? No severe cognitive impairment.

Exclusion criteria

Exclusion criteria: ? Progressive stroke; ? Subarachnoid hemorrhage; ? Bilateral stroke; ? Bilateral limb dysfunction; ? Other musculoskeletal and joint disorders that affect walking (such as fractures, osteoarthritis, etc.) and neurological disorders (such as tremors, involuntary movements, Parkinson's disease, etc.); ? Patients who have received other brain stimulation treatments (such as TMS) within the past two weeks or are currently undergoing treatment; ? There are contraindications for electrical stimulation therapy (such as pacemakers, local metal fixation, etc.); ? Concomitant serious heart, liver, kidney and other diseases; ? Traumatic brain injury, tumor, with a history of epileptic seizures or diagnosed with epilepsy Those who are unwilling to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Lower Limb Motor Score;FNIRS detection of changes in cerebral blood oxygen concentration;

Secondary

MeasureTime frame
Gait Watch 3D Gait Analysis;Funtional ambulation category;Modified Barthel index;

Countries

China

Contacts

Public ContactChen Peishun

Guangzhou Panyu Central Hospital

cpshun21@126.com+86 135 5610 2282

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026