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Effects of distal ischemic preconditioning combined with yiqi huoxue Zhitong recipe on myocardial perfusion and inflammatory factors in patients with coronary heart disease after percutaneous coronary intervention

Effects of distal ischemic preconditioning combined with yiqi huoxue Zhitong recipe on myocardial perfusion and inflammatory factors in patients with coronary heart disease after percutaneous coronary intervention

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080499
Enrollment
Unknown
Registered
2024-01-31
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

Control Group:Conventional Western Medicine+Placebo granules+ Blank pretreatment
Chinese medicine treatment group:Conventional Western Medicine+ Yiqi Huoxue Zhitong granule+ Blank pretreatment
Distal ischemic preconditioning combined with Yiqi huoxue Zhitong prescription group:Conventional Western Medicine+ Distal ischemic preconditioning+ Yiqi huoxue Zhitong granule

Sponsors

Guangdong Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: (1) patients aged 40-85 years were in accordance with the diagnostic criteria of Western medicine and TCM syndrome types. (2) patients were able to complete the treatment 2 days before PCI and 3 days after PCI. (3) the ability of expression and communication was normal. (4) complete coronary angiography and stent implantation. (5) informed consent was obtained.

Exclusion criteria

Exclusion criteria: (1) ALT, AST > 2 times the normal value, eGFR < 30ml/min/1.73, general condition of the whole body was poor. (2) patients with malignant arrhythmia, infection and serious imbalance of water and electrolyte were difficult to correct.

Design outcomes

Primary

MeasureTime frame
IL-6;CRP;

Secondary

MeasureTime frame
Blood pressure;Heart rate;Symptom grading quantification table;Canadian Cardiovascular Society (CCS) Angina Severity Scale;Adverse events;

Countries

China

Contacts

Public ContactHezhen Zhang

Guangdong Provincial Hospital of Traditional Chinese Medicine; Guangdong Provincial Hospital of Traditional Chinese Medicine Zhuhai Hospital

406363179@qq.com+86 136 7606 1716

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026