lung cancer
Conditions
Interventions
Low concentration nalbuphine group (LN group):The concentration of nalbuphine in the analgesic pump is 0.5mg/kg.
Medium concentration Nabupine group (MN group):The concentration of nalbuphine in the analgesic pump is 1mg/kg.
High concentration nalbuphine group (HN group):The concentration of nalbuphine in the analgesic pump is 1.5 mg/kg.
Control group:no
Sponsors
Taixing People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients of the American Society of Anesthesiologists physical status I to III, aged 18 to 80 years , Patients undergoing thoracoscopic lobectomy for lung cancer
Exclusion criteria
Exclusion criteria: Evidence of coagulation dysfunction Body mass index (BMI) less than 15 kg/m2 or greater than 30 kg/m2 Infection at the puncture site Patients with severe liver, renal, cardiovascular, diseasesmental illness, or self-expression disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting/Activity VAS Score;anesthesia time, intraoperative anesthetic dosage, postoperative wakefulness, tracheal intubation time, and PACU stay time; | — |
Secondary
| Measure | Time frame |
|---|---|
| serum levels of interleukin-1b and interleukin-6;Ramsay sedation score;the incidence of respiratory depression;the incidence of postoperative adverse reactions such as nausea, vomiting, dizziness, and skin itching; | — |
Countries
China
Contacts
Public ContactWang Cancan; Hu Xianwen
Taixing People's Hospital; The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed