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Detection of intraperitoneal free cancer cells from gastrointestinal tumors

New methods of detecting free cancer cells in abdominal cavity during gastrointestinal tumor operation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080490
Enrollment
Unknown
Registered
2024-01-30
Start date
2021-03-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer and colorectal cancer

Interventions

Gold Standard:cytology
Index test:CellCollector technology (CEA as marker), qPCR technology (CEA, lncRNA-GC1, GMAN, HOTTIP, SNHG1, NEAT1, SNHG6 and CCAL as markers)

Sponsors

Gastrointestinal Surgery Department,Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with gastric or rectal cancer confirmed by pathology in our hospital or other hospitals; no distant metastasis confirmed by preoperative imaging and feasible radical resection; no preoperative neoadjuvant radiotherapy; no other major underlying diseases; no comorbidities such as preoperative obstruction, bleeding or perforation.

Exclusion criteria

Exclusion criteria: Combination of other malignant tumors or previous history of malignant tumors; current history of uncontrollable infections or combination of major systemic diseases; distant metastases detected by preoperative imaging or intraoperative exploration

Design outcomes

Primary

MeasureTime frame
intraperitoneal free cancer cells;sensitivity;specificity;area under roc curve(AUC);

Secondary

MeasureTime frame
Positive Predictive Value;negative predictive value;

Countries

China

Contacts

Public ContactJianping Gong

Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology

jpgong@tjh.tjmu.edu.cn+86 134 3710 8081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026