Decreased ovarian reserve
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Meets diagnostic criteria for DOR; (2) 20 years old = Age = 45 years old; (3) 10 IU/L = FSH < 25 IU/L for two consecutive menstrual cycles (detected on the 2nd to 4th day of the menstrual cycle); (4) Sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Premature ovarian failure, early-onset ovarian insufficiency, and menopausal patients; (2) Chromosomal karyotype abnormalities; (3) Ovarian tumors, pituitary adenomas, congenital adrenal hyperplasia, Cushing's syndrome, thyroid dysfunction; (4) Those who have used hormones or simultaneously used hormone and metabolic drugs within the past 3 months have an impact on the judgment of results; (5) Uterine malformations such as unicorn uterus, double uterus, uterine septum, etc; (6) Patients with repeated implant failures; (7) Subjects who are currently participating in or have participated in other clinical trials within a month; (8) Patients with combined dysfunction of the heart, liver, and kidneys, or severe mental illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| anti-mullerian hormone;Antral follicle count ;follicle-stimulating hormone; | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved Kupperman rating scale;Luteinizing hormone;Positive pregnancy;Number of retrieved oocytes;Normal number of fertilizations;Number of transferable embryos and high-quality embryos; | — |
Countries
China
Contacts
Shandong University of Traditional Chinese Medicine