interstitial cystitis
Conditions
Interventions
Transurethral electrocautery + water dilatation treatment group:Firstly, hydrodilatation with saline is performed under general anaesthesia and Hunner's lesion is seen during this procedure. The crite
Non-transurethral electrocautery + water dilatation treatment group:Intravesical instillation of 2% (mass fraction) lidocaine 10 mL + 5% (mass fraction) sodium bicarbonate 5 mL + heparin 25,000 IU was
Sponsors
The First Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Combined with pain related to bladder filling/emptying, frequent urination, nocturia, and urinary urgency; 2. Cystoscopy under local anesthesia shows Hunner lesions or small globular hemorrhage of bladder mucosa; 3. Exclude other diseases with similar symptoms (such as infection, overactive bladder, or malignancy).
Exclusion criteria
Exclusion criteria: 1. The bladder capacity in the awake state is >350 mL; 2. There is still no strong sense of urgency when the bladder capacity reaches 150 mL, and urodynamics shows involuntary bladder contraction; 3. Anti-infectious, anti-microbial, anti-cholinergic and anti-inflammatory Spasm drugs can relieve symptoms; 4. The number of urinations during the day when awake is less than 8 times; 5. Routine urine examination and urinary tract B-ultrasound before treatment reveal inflammation, stones, tumors, vesicoureteral reflux and other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| interstitial cystitis patient symptom index scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| interstitial cystitis patient problem index scores;suprapubic pain visual analog scale; | — |
Countries
China
Contacts
Public ContactZhenming Jiang
The First Hospital of China Medical University
Outcome results
None listed