Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosed with COPD according to the Global Initiation of Lung Disease (GOLD) criteria (exertional expiratory volume in 1s (FEV1)/exertional lung capacity (FVC) <70%), and also in the GOLD stage I-II, with an age range between 50 and 80 years;
Exclusion criteria
Exclusion criteria: 1. inability to complete the questionnaires of our study due to cognitive impairment; 2. Difficulty in completing the cardiopulmonary exercise test (CPET) or the 6-minute walk test (6MWT); 3. Patients with severe cardiovascular or cerebrovascular disease, hepatic or renal insufficiency, epilepsy and other neuropsychiatric disorders, etc., which are assessed by the investigator as not easily amenable to this study; 4. patients with severe combined lung cancer, tuberculosis, interstitial fibrosis, severe alveoli, pneumothorax, history of thoracic and abdominal surgery, etc., which the investigator considers to affect the observation of the efficacy of the treatment or the risk of performing pulmonary rehabilitation exercises; 5. pleural disease or thoracic deformity; 6. severe cognitive impairment/dementia (Montreal Cognitive Assessment score <17) or neuropsychiatric symptoms of other diagnoses .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxy-hemoglobin;Deoxy-hemoglobin;Total hemoglob; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diffusing Capacity of the Lung for Carbon Monoxide;Forced Vital Capacity;Forced expiratory volume in one second;maximal inspiratory pressure;Maximal expiratory pressure;Partial Pressure of Oxygen in Arterial Blood;Partial Pressure of Carbon Dioxide in Arterial Blood; | — |
Countries
China
Contacts
Anqing Normal University