Blood type and transfusion
Conditions
Interventions
Infusion of red blood cells group - experimental group:Patients and blood donors were identified by ABO blood grouping and RHCcEe typing, and blood components with the same RH typing were selected for
Infusion of red blood cells group - control group:Patients and blood donors were routinely blood typed for ABO blood grouping and RHD type, cross-matched and then transfused for compatibility.
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
60 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1: Age greater than or equal to 60 years 2: Need for at least one transfusion of red blood cells during hospitalization 3: Subject (or the patient's legal representative) has signed an informed consent form
Exclusion criteria
Exclusion criteria: 1: Patients with significant uncontrollable overt blood loss requiring urgent resuscitation 2: Patients with severe ischemic cardiovascular disease or ventilatory dysfunction 3: Patients whose first irregular antibody screening suggests the presence of non-specific blood group antibodies (e.g. autoantibodies) that make blood matching difficult 4: Patients with special or rare blood types (subtype A or Rh D-negative patients, etc.) 5: Patients who have participated in other clinical studies (e.g., clinical studies such as cell therapy) within 2 months prior to the start of the study 6: Patients or their legal representatives are unwilling to sign a written informed consent or to comply with the study protocol
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin count;erythrocyte count;erythrocyte pressure;Mean erythrocyte volume;Mean red cell hemoglobin;Mean red cell hemoglobin concentration; | — |
Secondary
| Measure | Time frame |
|---|---|
| erythrocyte distribution width; | — |
Countries
China
Contacts
Public ContactMa Wanru
Beijing Hospital
Outcome results
None listed