Septic cardiomyopathy
Conditions
Interventions
Sepsis cardiomyopathy group:None
Non sepsis cardiomyopathy group group:None
Sponsors
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) 18 years old =Age=80 years old 2) Infection (increased CRP/PCT) +SOFA score =2 points 3) Ejection fraction <50% and left ventricular ejection fraction LVEF decreased by 10% from baseline 4) Increased levels of plasma BNP and NT-proBNP
Exclusion criteria
Exclusion criteria: 1)Subjects/family members declined to participate in the study 2)Previous heart disease 3)previous thrombocytopenia/thrombocythemia; 4)During the treatment, blood transfusion and other blood products of others were used 5)The use of hemostatic drugs and antiplatelet drugs affect platelet function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of platelet exosomes in subjects; | — |
Secondary
| Measure | Time frame |
|---|---|
| Subject's blood routine platelet count, thromboelastogram, cardiac ultrasound; | — |
Countries
China
Contacts
Public ContactWangning ShangGuan
The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Outcome results
None listed