Helicobacter pylori infection
Conditions
Interventions
Probiotic group:Taking probiotics to inactivate bacteria
Sponsors
Changhai Hospital (The First Affiliated Hospital of Naval Medical University)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? Patients diagnosed with Helicobacter pylori infection by 13C/14C breath test, rapid urease test or histological examination; ?18 to 65 years old, male and female half; ?The patient has no history of serious disease (such as malignant tumor) or upper gastrointestinal tract (such as cardiac bradycardia); ?Promise to cooperate with the study throughout the experimental period; ? Willing to provide written informed consent and basic information questionnaire; ? No previous anti-pyloric therapy, and no antibiotics or probiotics in the month before inclusion in the study.
Exclusion criteria
Exclusion criteria: ? History of gastrointestinal surgery (except appendectomy); ? Pregnant or lactating women; ?Have any historical serious disease (serious cardiovascular, endocrine, liver and kidney dysfunction, etc.); ?Patients were also excluded if they had taken antibiotics or probiotics in the month prior to inclusion; ? Subjects participating in other clinical trials; ? Unwilling or unable to provide written informed consent to participate in the study after the researcher has notified the researcher of the purpose, process and possible risks; ? Those who do not meet the requirements of the study or the researchers think that they should not participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 13C Urea breath test;Blood biochemical examination;Fecal genome;Serum pepsinogen; | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum TNF-a;IL-6IL-8; | — |
Countries
China
Contacts
Public ContactLi Minyu
Changhai Hospital
Outcome results
None listed