Hepatocellular carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Patients with CNLC - stage III / bclc-c hepatocellular carcinoma; ? Liver function grade child Pugh A; ? ECOG-ps 0 or 1 point; ? 18-75 years old; ? The expected survival time was more than 3 months; ? There was no history of gastrointestinal bleeding in recent 6 months; ? No previous PD-1 antibody treatment; ? For patients beyond the above inclusion criteria, exploratory treatment can be carried out gradually according to the specific situation; ? Sign the informed consent form and agree to participate in the clinical study.
Exclusion criteria
Exclusion criteria: ? PD-1 antibody was used before the study. ? The basic constitution is extremely weak, so it is impossible to take clinical programs other than conservative treatment. ? Have a history of autoimmune diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| odds ratio; | — |
Secondary
| Measure | Time frame |
|---|---|
| objective response rate; | — |
Countries
China
Contacts
Air Force Medical Center, PLA