Frailty
Conditions
Interventions
Treatment group:Standard Western medicine and Warming Spleen and Reducing Turbidity Decoction
Control group:Standard Western medicine
Sponsors
Guang’anmen Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 30-80 years of age, gender not limited; (2) The glucolipid metabolic disorder and CHF diagnosis standard, cardiac function class (NYHA) ? - ?; (3) Comply with the Fried weak phenotypic 3 and above; (4) The diagnostic criteria of spleen deficiency and phlegm turbid syndrome; (5) Voluntary participants subjects and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) Caused by primary diseases (chronic kidney disease, chronic liver disease, hypothyroidism) of blood sugar, blood lipid abnormalities. (2) A diagnosis of type 1 diabetes, gestational diabetes, or other special types of diabetes. (3) The result of valvular heart disease, congenital heart disease, myocarditis caused by heart failure; (4) In acute coronary syndrome, severe arrhythmia and always happens every source sex shock; (5) And severe liver function abnormal ALT and AST (more than three times the upper limit of normal) or abnormal renal function (estimated glomerular filtration rate < 30 ml/min / 1.73 m2); (6) Patients with malignant tumors or autoimmune diseases; (7) Visual impairment, hearing disabled or cognitive impairment, and patients who are unable to cooperate with the scale test; (8) Allergic constitution and allergy to the components of the drug used in this study; (9) Be in other clinical trials or involved in other drugs clinical experiment is over not more than 1 months; (10) Women in pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Short Physical Performance Battery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Kansas City Cardiomyopathy Questionnaire; Montreal Cognitive Assessment ;Geriatric Depression scale;Fasting blood glucose;2 hours postprandial blood sugar;HbA1c;total cholesterol;triglyceride;high-density lipoprotein;low-density lipoprotein;NT-proBNP;cTNI;Cardiac ultrasound;tumor necrosis factor-a;interleukin-6;interleukin-10;hsCRP;Monocytechemoattractantprotein-1;Intestinal flora; | — |
Countries
China
Contacts
Public ContactLi Yumeng
Guang’anmen Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed