general anesthesia
Conditions
Interventions
Dex group (experimental):Dexmedetomidine was pumped after induction and maintenance of general anesthesia with sevoflurane
Saline group (control):Normal saline was pumped after induction and maintenance of general anesthesia with sevoflurane
Sponsors
Shengjing Hospital of China Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1: Plan to undergo selective non-craniocerebral and non-cardiac pediatric surgery under general anesthesia 2: Aged 2-12 years 3: Full-term delivery 4: Procedures were 2 hours or longer 5: ASA score is ?~?
Exclusion criteria
Exclusion criteria: 1: There were growth retardation, cerebrovascular accident, mental illness, severe cognitive impairment, epilepsy and other nervous system Systematic adverse events 2: Parents with conditions that hinder communication and preoperative evaluation, such as severe hearing or vision impairment 3: Previous history of general anesthesia surgery 4: Patients with head trauma/infection, severe eczema, skin allergy or allergy are not suitable for EEG monitoring 5: Preoperative infusion of sedatives (less than 24 hours), including propofol, morphine, fentanyl, midazolam, chloramine Ketone and dexmedetomidine 6: Patients who are known to be allergic to the active ingredient of dexmedetomidine, or have contraindications to the use of dexmedetomidine such as heart disease Bradykinesia, hypotension or severe cardiac dysfunction 7: Emergency surgery or parents refused to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electroencephalogram parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Richmond Agitation-Sedation Scale, RASS;Pain-Numerical rating scale;The Post-Hospitalisation Behaviour Questionnaire, PHBQ;The Strengths and Difficulties Questionnaire, SDQ;postoperative complications; | — |
Countries
China
Contacts
Public ContactMeiying Cui
Shengjing Hospital of China Medical University
Outcome results
None listed