Thoracotomy
Conditions
Interventions
Epidural anesthesia group:Unilateral epidural anesthesia
General anesthesia group:Paravertebral intercostal nerve block
Sponsors
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Thoracotomy patients, including: esophagus, lung, mediastinum and other diseases. 2. Age 18-75 years old. 3. The ASA classification is in grade I ~ III. 4. There was no history of chronic pain before surgery. 5. Preoperative cardiopulmonary function was normal (NYHA grade ?, EF >50%, FEV1/FVC>70%).
Exclusion criteria
Exclusion criteria: 1. Infection at the puncture site. 2. Combined with central or peripheral neuropathy. 3.The patient has contraindications for surgery, such as serious cardiopulmonary disease and coagulation dysfunction. 4. Senile dementia, cerebral atrophy, acute phase or sequelae of cerebrovascular disease, cognitive impairment. 5. Local or systemic acute infection failed to effectively control. 6. Combined with shock and critical illness, unable cooperate with the operation and effect evaluation. 7. Mental and neurological diseases unable cooperate with the doctor. 8. Patients with a history of allergy to narcotic drugs. 9. Long-term use of opioid analgesics. 10. Chronic alcoholics. 11. Postoperative deterioration and second operation. 12. Other situations in which are inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative ephedrine use;Temporary analgesic drug use;Hemodynamics;Cutaneous sensory change; | — |
Countries
China
Contacts
Public ContactYida Liao, Guangmin Xu
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
Outcome results
None listed