none
Conditions
Interventions
morphine group (M3):3mg epidural morphine
morphine group (M4):4mg epidural morphine
morphine group (M1):1mg epidural morphine
morphine group (M2):2mg epidural morphine
control group (M0):transversus abdominis plane block (TAP) in combination with PCIA for postoperative pain management.
Sponsors
West China Second University Hospital, Sichuan University
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1) ASA I-II healthy pregnant women; 2) age =18 years old; 3) Elective cesarean section under combined spinal and epidural anesthesia; 4) Signed the informed consent form
Exclusion criteria
Exclusion criteria: 1) Emergency or other unplanned cesarean section; 2) Contraindications of neuraxial anesthesia; 3) Body mass index (BMI) =40kg/m^2; 4) Previous neurological diseases (cerebral hemorrhage, cerebral infarction or transient ischemic attack, etc.) 5) Past or existing heart-related disease; 6) With hypertension, use magnesium, etc.; 7) Known or suspected sleep apnea syndrome (OSAS); 8) Long-term use of opioids or psychotropic drugs; 9)Difficulty with language expression, refusal to participate in the experiment or failure to cooperate with the interviewer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of NRS-Move =4 within 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of NRS-Move =4 within 48 hours after surgery; | — |
Countries
China
Contacts
Public ContactXuemei Lin
West China Second University Hospital, Sichuan University
Outcome results
None listed