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Observation on the effect of local injection of butorphanol combined with ropivacaine for postoperative analgesia in patients undergoing daytime laparoscopic cholecystectomy

Observation on the effect of local injection of butorphanol combined with ropivacaine for postoperative analgesia in patients undergoing daytime laparoscopic cholecystectomy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400080338
Enrollment
Unknown
Registered
2024-01-26
Start date
2024-02-01
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cholecystolithiasis

Interventions

trial group:Before the end of the surgery, after the gallbladder is removed, the incision site is infiltrated with 20ml of 0.33% ropivacaine combined with 2mg of butorphanol mixture, including 10ml of
control group:Before the end of the surgery, after the gallbladder is removed, 20ml of 0.33% ropivacaine is used for incision infiltration at the surgical incision site, with 10ml of periumbilical inc

Sponsors

Qionglai Medical Center Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1) Age range from 18 to 60 years old, regardless of gender; 2) Voluntarily accept the experiment and sign the consent form for surgery and anesthesia; 3) ASA grade I-II, planned for daytime laparoscopic cholecystectomy surgery;

Exclusion criteria

Exclusion criteria: 1) Patients with central nervous system diseases or respiratory dysfunction; 2) Uncontrolled hypertension; Heart disease (i.e. those with a heart function of level III or above); Significant abnormalities in liver and kidney function (i.e. indicators higher than twice the normal value). 3) People who are highly sensitive to butorphanol tartrate and chlorpheniramine; 4) Drug or alcohol abusers; 5) Participated in other clinical trials within 4 weeks prior to the start of the study; 6) Individuals who are currently taking or have taken MAO inhibitors (such as Eugenin, Phenylhydrazine, etc.) within 2 weeks prior to the start of this experiment; 7) During surgery, there may be significant bleeding or prolonged surgery time, or the surgery may be terminated due to other reasons.

Design outcomes

Primary

MeasureTime frame
visual analogue scale;

Secondary

MeasureTime frame
Ramsay Sedation score;Nausea and vomiting score;

Countries

China

Contacts

Public ContactLiu Ting

Qionglai Medical Center Hospital

1048471944@qq.com+86 153 9043 9690

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026