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Clinical study on the effect of monocular surgical neurotomy on the ocular surface microenvironment and nerves of both eyes in patients with keratoconus

Clinical study on the effect of monocular surgical neurotomy on the ocular surface microenvironment and nerves of both eyes in patients with keratoconus

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080334
Enrollment
Unknown
Registered
2024-01-26
Start date
2024-03-15
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keratoconus

Interventions

Femtosecond laser-assisted partial LKP group:Partial lamellar keratoplasty
Corneal stromal implantation group:Corneal stromal implantation is performed
Corneal cross-linking group:Corneal cross-linking therapy is performed

Sponsors

Eye Hospital of Shandong First Medical University (Shandong Eye Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
10 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) Age 10-70 years; (2) All cases diagnosed with femtosecond laser-assisted partial lamellar keratoplasty, corneal stromal implantation, and corneal cross-linking therapy for keratoconus were included in the analysis. (3) No contraindications such as active inflammation, dry eye, strabismus, glaucoma, fundus disease, etc.; (4) No systemic immune diseases, diabetes, or mental illnesses.

Exclusion criteria

Exclusion criteria: (1) Suffering from eye diseases such as active inflammation, dry eye, strabismus, glaucoma and fundus disease; (2) Immune system disorders, diabetes, and psychiatric disorders.

Design outcomes

Primary

MeasureTime frame
confocal microscopy;Corneal perception;Schirmer Test;Tear film break-up time;

Secondary

MeasureTime frame
Meibomian gland photography;

Countries

China

Contacts

Public ContactHua Gao

Eye Hospital of Shandong First Medical University (Shandong Eye Hospital)

gaohua100@126.com+86 531 8127 6006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026