population health
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? health; ? Adults aged 18-45 years ; ? 18.5 kg/m2 < BMI < 30 kg/m2; ? Able to sign informed consent and voluntarily participate, willing to accept questionnaire surveys; ? Regular diet, normal eating habits, and regular sleep schedule; ? Able to estimate daily diets and record relevant information according to the experimental requirements during the survey period.
Exclusion criteria
Exclusion criteria: BMI 30 kg/m2; ? Pregnant or planning to become pregnant; ? Vegetarian, irregular diet, abnormal eating habits, or plans to lose weight in the short term; ? Immunodeficiency, HIV infection; ? Post-operative patients with gut loss, gastrointestinal anatomical changes; ? Patients with gastrointestinal functional disorders, chronic gastrointestinal diseases (such as diarrhea, constipation), or acute gastrointestinal diseases that affect gastrointestinal function and still require drug treatment (such as acute or acute digestive tract ulcer disease); ? Patients with diagnosed gastrointestinal tumors, diabetes, respiratory system diseases, cardiovascular and cerebrovascular diseases, hyperglycemia, hyperlipidemia, hypertension, cancer or tumors; ? Fever or infection within the past week, or oral or intravenous administration of antibiotics, hormones, anti-inflammatory drugs (steroids such as prednisone, methylprednisolone, hydrocortisone, betamethasone, dexamethasone, etc.), non-steroidal anti-inflammatory drugs (such as aspirin, acetaminophen, ibuprofen); ? Use of probiotics, prebiotics, or other microbiological preparations within 2 weeks, or use of dietary supplements in the past month and during the observation period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24-hour dietary record every day.;Gut microbiota.;Inflammatory factor mRNA expression levels;Inflammatory factor protein expression levels;Blood biochemical indicators (routine blood test, CRP, blood glucose, blood lipids, uric acid).; | — |
Secondary
| Measure | Time frame |
|---|---|
| General information: including age, gender, ethnicity, marital status, occupation, income, medical history, smoking history, alcohol consumption history, dietary habits, sleep schedule.;Daily sleep and meal schedule.;height;Weight;Human composition;Blood pressure;Waist circumference;Hip circumference; | — |
Countries
China
Contacts
School of Public Health, Guangxi Medical University