Breast cancer
Conditions
Interventions
Gold Standard:Surgical pathological diagnosis or biopsy pathological diagnosis.
Index test:Sonazoid Contrast-enhanced Ultrasound
Sponsors
Sun Yat-sen University Cancer Center
Eligibility
Sex/Gender
Female
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Age greater than or equal to 18 years old. 2) Available to choose the diagnosis and treatment method independently, and obtain the signing of the informed consent form. 3) Patients with T1/2 stage breast cancer that have been pathologically diagnosed. 4) Patients classified as 4C or 5 by ultrasound BI-RADS. 5) Axillary lymph nodes can be confirmed pathologically.
Exclusion criteria
Exclusion criteria: 1) Pregnant or lactating women. 2) Patients with contraindications for Sonazoid contrast-enhanced ultrasonography. 3) Patients with contraindications for both CT and MRI. 4) Patients who cannot tolerate surgery or puncture. 5) Patients whose biopsy results are not breast cancer. 6) Patients with unstable clinical status, advanced disease or unpredictable clinical course. 7) Patients with a history of breast cancer or other malignant tumors. 8) Patients who have received the study drug within 30 days before the contrast-enhanced ultrasound or need to receive the study drug within 72 hours after the contrast-enhanced ultrasound.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasound appearance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Positive predictive value; | — |
Countries
China
Contacts
Public ContactJianhua Zhou
Sun Yat-sen University Cancer Center
Outcome results
None listed