Cognitive impairment in schizophrenia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Subject informed consent; (2) = 18 years old, male; (3) Having good auditory and visual abilities; (4) Diagnostic criteria for chronic schizophrenia in accordance with DSM-4; (5) For patients with a disease course of = 5 years, hospitalization of = 1 year, and long-term use of antipsychotic drugs, the rehabilitation period meets clinical standards, with a positive and negative symptom scale (PANSS) score not exceeding 60 points.
Exclusion criteria
Exclusion criteria: (1) Organic brain diseases, epilepsy, individuals with low intelligence, and other serious physical illnesses; (2) History of head injury, loss of consciousness for more than 30 minutes; IQ less than (including) 90 points; (3) Patients with severe excitement, impulsiveness, and lack of cooperation; (4) Those who are unwilling to participate in the survey; (5) History of intake of psychoactive substances;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cambridge Neuropsychological Test Automated Battery-Reaction Time;Cambridge Neuropsychological Test Automated Battery-Spatial Working Memory;Cambridge Neuropsychological Test Automated Battery-Paired Associates Learning; | — |
Secondary
| Measure | Time frame |
|---|---|
| The positive and negative syndrome scale;Self-report quality of life measure for people with schizophrenia;Personal and Social Performance Scale;Clinical Global Impression;Treatment Emergent Symptom Scale;Snaith-Hamilton Scale;Dimensional Anhedonia Rating Scale; | — |
Countries
China
Contacts
Department of Psychiatry, The First Affiliated Hospital of Chongqing Medical University