Effect of Low-dose Supplemented Dexmedetomidine on Postoperative Short-term and Long-term Sleep Quarlity During Gynecological Laparoscopic Surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400080267

Enrollment

Unknown

Registered

2024-01-25

Start date

2024-01-25

Completion date

Unknown

Last updated

2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep-wake disorder

Interventions

Dexmedetomidine group:After induction of general anesthesia by conventional tracheal intubation, the patient was given 0.3ug/ (kg·h) continuous intravenous pumping of dexmedetomidine for 30 minutes.Pa

Control group :After induction of general anesthesia with routine tracheal intubation, the patient was given 0.9% normal saline of the same volume for 30 minutes.Patients' sleep was monitored from 20:

Eligibility

Sex/Gender

Female

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1)Age 18-65 years old; (2)ASA I-II level; (3)Patients undergoing laparoscopic reproductive surgery;(4) This study must be approved by the Ethics Committee of the hospital, and all patients participating in the study must sign the informed consent of anesthesia and experiment.

Exclusion criteria

Exclusion criteria: (1)Patients refused to participate in the study; (2)Body mass index (BMI) greater than 30; (3)There is a clear history of mental sleep problems in the past (depression, schizophrenia, sleep disorders, PSQI > 7 score 17) or a family history of sleep problems in the second line of three generations; (4)Cognitive or communication impairment; (5)A recent history of substance abuse; (6)Contraindications or dexmedetomidine allergy; (7)Cognitive impairment or inability to communicate; (8)In the past week, I have used central nervous system stimulants, sedatives, analgesics, hypnotics and drugs with similar pharmacological effects.

Design outcomes

Primary

Measure	Time frame
Incidence of sleep disorders on the first day after surgery;	—

Secondary

Measure	Time frame
Numeric rating scale of sleep after surgery;Visual analogue pain score 72 hours after surgery;Use of sedative and analgesic drugs 72 hours after surgery;Pittsburgh Sleep Quality Index score after surgery;Insomnia Severity Index score after surgery;Self-Rating Anxiety Scale score after surgery;	—

Countries

China

Contacts

Public ContactLili Xu

Women's Hospital School of Medicine Zhejiang University

xulili@zju.edu.cn+86 182 6814 4502

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026