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Clinical study of Xijiao Dihuang decoction and Erzhi Pill in preventing thrombocytopenia related to chemotherapy

Clinical study of Xijiao Dihuang decoction and Erzhi Pill in preventing thrombocytopenia related to chemotherapy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080265
Enrollment
Unknown
Registered
2024-01-24
Start date
2022-09-01
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Chemo, thrombocytopenia

Interventions

Experimental group (Routine chemotherapy regimen plus rhinoceros horn and Rehmannia decoction heerzhi pills were given):None
Control Group (Routine chemotherapy regimen):None

Sponsors

San Huan Cancer Hospital, Chaoyang District
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.18-70-year-old patients with solid tumors (breast, lung, esophageal, stomach, colorectal, pancreatic, etc.) who received their first chemotherapy with platinum-based combination chemotherapy, including but not limited to neoadjuvant chemotherapy, adjuvant chemotherapy, first-line therapy, etc. ; 2.ECOG 0-2 points; 3 informed consent, willing to participate in this study; 4 baseline laboratory data: platelet count =100 × 10 ^ 9/l; 5 the main organ functions were tolerant to chemotherapy (liver, heart, kidney, lung, bone marrow function, etc.) , 6 the expected survival time was =12 weeks at screening, and the patients could receive at least one cycle of the current chemotherapy regimen.

Exclusion criteria

Exclusion criteria: 1 excluding patients with primary thrombocytopenia and other hematological disorders, 2 bone marrow involvement, 3 comorbidity with hematological disorders, 4 active bleeding or thrombosis, and 3 screening for thrombocytopenia 5 use of other bone marrow stimulators during treatment; 6 patients with uncontrolled or severe cardiovascular disease; patients unable to take oral medications; 7 pregnant or lactating women; 8 the researchers considered that participation in the trial had a greater risk or potential impact on the health or safety of the subjects.

Design outcomes

Primary

MeasureTime frame
Platelets;

Secondary

MeasureTime frame
Blood biochemical test;

Countries

CHINA

Contacts

Public ContactYurong Zhang

San Huan Cancer Hospital, Chaoyang District

sanhuanzyr@126.com+86 139 1079 5239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026