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Effects of different cytokines on microfluidic biomimetic vascular endothelial injury and function

Effects of different cytokines on microfluidic biomimetic vascular endothelial injury and function

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400080257
Enrollment
Unknown
Registered
2024-01-24
Start date
2024-04-01
Completion date
Unknown
Last updated
2024-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cytokine

Interventions

IL-6:High concentration IL-6 stimulated microfluidic biomimetic microvascular model
MCP-1:High concentration MCP-1 stimulated microfluidic biomimetic microvascular model
TNF-a:High concentration TNF-a stimulated microfluidic biomimetic microvascular model
IL-10:High concentration IL-10 stimulated microfluidic biomimetic microvascular model

Sponsors

Central Hospital of Dalian University of Technology
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Informed consent of pregnant women

Exclusion criteria

Exclusion criteria: Declined to use umbilical cord research

Design outcomes

Primary

MeasureTime frame
Expression of Endothelium VCAM;Expression of Endothelium eNOS;Expression of Endothelium ZO-1;Calyx thickness;—

Countries

China

Contacts

Public ContactYang Rongli

Central Hospital of Dalian University of Technology

yever3000@yeah.net+86 159 0496 3796

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026