None
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? Women aged 18-60; ? The skin is in good condition without any form of allergy and inflammation; ? The elasticity value of cheek skin should less than 0.600; ? Work, rest and eat healthily; ? No relevant treatment such as skin improvement has been carried out; ? Volunteer to participate in the test and sign the informed consent form.
Exclusion criteria
Exclusion criteria: ? Any form of allergy on the skin; ? Skin improvement and other related treatments are under way; ? Medical and aesthetic treatment or any kind of skin surgery were performed 3 months before enrollment; ? Have a history of genetic diseases, work and rest disorders, spicy diet and other bad habits.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Moisture content of facial skin cuticle;Oil content of facial skin;Facial skin elasticity;PH of facial skin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Diversity of gut microbiota;Intestinal metabolites;Blood MDA;Blood NO;Blood SOD;Blood MMP9; | — |
Countries
China
Contacts
China Agricultural University